Biggle was born in 1923 in Waterloo, Iowa. He served in World War II as a communications sergeant in a rifle company of the 102nd Infantry Division; during the war, he was wounded twice. His second wound, a shrapnel wound in his leg received near the Elbe River at the end of the war, left him disabled for life.

After the war, Biggle resumed his education. He received an A.B. Degree with High Distinction from Wayne State University and M.M. and Ph.D. degrees from the University of Michigan. Biggle taught at the University of Michigan and at Eastern Michigan University in the 1950s. He began writing professionally in 1955 and became a full-time writer with the publication of his novel, All the Colors of Darkness in 1963; he continued in the writing profession until his death.